• Anglický jazyk

Tectona Grandis - A Useful Herb

Autor: Jitendra Bhangale

The aqueous extract of Tectona grandis bark (ATG) was investigated for anti-inflammatory and antinociceptive activity at the doses (p.o.) of 100, 200 and 400 mg/kg body weight. The acetic acid-induced writhing response, tail immersion test and hot plate... Viac o knihe

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O knihe

The aqueous extract of Tectona grandis bark (ATG) was investigated for anti-inflammatory and antinociceptive activity at the doses (p.o.) of 100, 200 and 400 mg/kg body weight. The acetic acid-induced writhing response, tail immersion test and hot plate test were used to assess antino-ciceptive activity. For evaluation of anti-inflammatory activity, carrageenan induced paw edema served as acute model. At a dose, ATG (100, 200 and 400 mg/kg, p.o.) significantly attenuated the writhing responses induced by an intraperitoneal injection of acetic acid and at ATG (200 and 400 mg/kg, p.o.) significantly increased pain latencies in tail immersion and hot plate test. In addition, the higher doses of ATG (200 and 400 mg/kg, p.o.) were inhibited carrageenan induced paw edema. From acute oral toxicity studies (OECD-423 guidelines), no mortality was observed even at highest dose of ATG (2000 mg/kg, p.o.).

  • Vydavateľstvo: LAP LAMBERT Academic Publishing
  • Rok vydania: 2012
  • Formát: Paperback
  • Rozmer: 220 x 150 mm
  • Jazyk: Anglický jazyk
  • ISBN: 9783659000607

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