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Anglický jazyk
CD4+CD25+T cells in HCV patients & Prevalence of Bacterial infection
Autor: Samira R. Mansour
CD4+CD25+Treg lymphocytes are a subset of circulating CD4+T cells with suppressive properties. CD4+CD25+ Treg cells suppress HCV-specific T cell responses. They may play a role in viral persistence. Our study was designed to assess the frequency of Treg... Viac o knihe
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O knihe
CD4+CD25+Treg lymphocytes are a subset of circulating CD4+T cells with suppressive properties. CD4+CD25+ Treg cells suppress HCV-specific T cell responses. They may play a role in viral persistence. Our study was designed to assess the frequency of Treg cells as well as occurrence of bacterial infection in different clinical presentation of HCV infection in a chosen Egyptian population. Data obtained showed high significant frequency of CD4+CD25+Treg cells in all HCV patients in comparable to healthy individuals. Conversely, within different clinical degrees of HCV infection no significant differences were detected. Higher Frequency of CD4+CD25+ Treg cells detected in HCV patients than in normal individuals may help to be used as a marker for early detection of viral disease and open new area to find a way to disease recovery/protection. The prevalence of bacterial infection among HCV patients was significant high as detected in both blood and urine samples specially among those with late disease episode. Staphylococcus aureus and ß-hemolytic Streptococcus viridanse were the common infected organisms in blood samples of HCV patients. In urine samples, Escherichia coli was detected.
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2012
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783659293467
