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Anglický jazyk
Electrostatic Considerations in Mitosis
Autor: L. John Gagliardi
Identifying the motive force is central to explaining chromosome motions during mitosis. Presently, there is no consensus on what it is. The author has proposed a minimal assumptions model for the dynamics of post-attachment chromosome motions based on nanoscale... Viac o knihe
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O knihe
Identifying the motive force is central to explaining chromosome motions during mitosis. Presently, there is no consensus on what it is. The author has proposed a minimal assumptions model for the dynamics of post-attachment chromosome motions based on nanoscale electrostatics. Given the electrical properties of tubulin and the dynamic instability of microtubules, it is possible to account for prometaphase post-attachment, metaphase, and anaphase chromosome motions within a comprehensive model. The model addresses all of the following in a unified manner:
Efficiency of aster and spindle assembly and the motive force for the motion of asters and forming half-spindles.
Chromatid pair attachment.
Motion of monovalently attached chromatid pairs.
Motion of bivalently attached chromatid pairs and chromosome congression.
Metaphase chromatid pair oscillations.
Chromatid separation and anaphase-A chromosome motion.
Anaphase-B pole separation.
An ab-initio calculation of the maximum tension force exerted by a microtubule during mitosis that falls within the experimental range.
Poleward force generation of chromosomes at poles with associated microtubule flux.
- Vydavateľstvo: iUniverse
- Rok vydania: 2009
- Formát: Paperback
- Rozmer: 229 x 152 mm
- Jazyk: Anglický jazyk
- ISBN: 9781440173783
