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Anglický jazyk
ERVWE1
Autor: Lambert M. Surhone
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. HERV-W_7q21.2 provirus ancestral Env polyprotein also known as Env-W or enverin or syncytin is a protein that in humans is encoded... Viac o knihe
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O knihe
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. HERV-W_7q21.2 provirus ancestral Env polyprotein also known as Env-W or enverin or syncytin is a protein that in humans is encoded by the ERVWE1 gene.Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
- Vydavateľstvo: OmniScriptum
- Rok vydania: 2026
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9786136412771
