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Anglický jazyk
Extrusion-Spheronization VS Solution / Suspension Layering Technique
Autor: Prateek Kulshrestha
Purpose: The purpose of this study is to formulate itopride hydrochloride sustained release pellets by Extrusion-Spheronization and Solution/ Suspension layering technique and to compare the pellet characteristics prepared from both the techniques. Methods:... Viac o knihe
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O knihe
Purpose: The purpose of this study is to formulate itopride hydrochloride sustained release pellets by Extrusion-Spheronization and Solution/ Suspension layering technique and to compare the pellet characteristics prepared from both the techniques. Methods: In the Extrusion-Spheronization technique, the drug pellets were prepared by mixing the drug with excipients along with a binder solution, the resultant mass was extruded through extruder followed by spheronizer. In Solution/suspension layering technology the pellets were prepared by coating the drug solution/suspension on the sugar spheres in a fluidized bed processor (FBP). The prepared drug pellets from both the techniques were seal coated with HPMC 5cps followed by sustained release coating of Ethyl cellulose 7cps in the FBP.
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2018
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783659635984
