Carpenter, G: Pediatrics, Vol. 2

Excerpt from Pediatrics, Vol. 2: Devoted to the Diseases of Children; November 2nd, 1896

Werlhoffii. Certain of the cases are secondary to some acute specific fever or other infective disorder; but a large number remains, which must be considered at present as primary or idiopathic, in the absence of any knowledge of their aetiology or pathology. Until this knowledge is forthcoming we must be content to classify them according to their clinical signs and symptoms. Proceeding on these lines Henochl, in 1874, recorded a series of cases characterized by purpura with colic, vomiting, intestinal haemorrhage, rheumatoid pains, and, less constantly, swelling of the joints. In 1876 Couty2 published some more cases, the leading symptoms of which were pur puric outbreaks, gastro-intestinal troubles, and cutaneous oedema. He regarded the affection as nervous in origin, and dependent on an irritative lesion of the sympathetic system, comparable to some extent to that seen in lead poisoning. In 1890 Dusch and Hoche3 made a careful study of all the re corded cases and came to the conclusion that the form of pur pura described by Henoch is to be regarded as a well defined and distinct affection. In Germany and in America this dis ease is now known by the name of Henoch's Purpura, but in England it does not seem to have attracted much attention. Two very typical cases were recorded by Bristowe4 in 1885, under the title Purpura Urticans, as they appeared to him to resemble the affection described by Willan under that name. The patients were boys, aged respectively ten and fifteen years, who suffered from abdominal pain, melaena hzematuria, and a purpuric eruption on the extremities.

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