• Anglický jazyk

Intracellular Signal Transduction: The JAK-STAT Pathway

Autor: Andrew F. Wilks

This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These... Viac o knihe

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O knihe

This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.

  • Vydavateľstvo: Springer
  • Rok vydania: 2013
  • Formát: Paperback
  • Rozmer: 254 x 178 mm
  • Jazyk: Anglický jazyk
  • ISBN: 9783662220528

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