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Anglický jazyk
Thiocillin I
Autor: Virender Aulakh
Over the past half century, the absolute configuration of thiopeptide antibiotics such as Thiocillin I has baffled chemists until the first correct synthesis of Micrococcin P1 in 2009. At this point we had to answer two questions - first, does the absolute... Viac o knihe
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O knihe
Over the past half century, the absolute configuration of thiopeptide antibiotics such as Thiocillin I has baffled chemists until the first correct synthesis of Micrococcin P1 in 2009. At this point we had to answer two questions - first, does the absolute configuration hold true for its natural analogues? Second, can we design a more efficient synthesis of the tri-substituted pyridine core? The current synthesis sheds light on these problems especially for medicinal chemists who wish to explore the SAR for the purposes of drug development.
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2011
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783844391008
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